Figure 1
From: Modulation of dendritic cell function by the radiation-mediated secretory protein γ-synuclein
SNCG was increased by irradiated breast cancer cell lines. (a and b) Human breast cancer cell lines (MDA-MB231 and MCF-7) were exposed to 5 or 10 Gy doses of γ-irradiation, and the expression of SNCG was detected by western blotting at 24, 48 and 72 h after radiation. (c and d) The viability of MDA-MB231 and MCF-7 cells was determined by an MTT assay. (e and f) The secreted SNCG was detected in the conditioned media from MDA-MB231 and MCF-7 cells using immunoblotting. The data represents the mean ± S.D. of three independent experiments. ###P<0.001 was compared with 24h 0 Gy group; while ***P<0.001 and *P<0.05 were compared with the 0 Gy group in their seperate time frames. Significance was determined by one-way ANOVA followed by Tukey's multiple comparison tests.
