Figure 3
From: mTORC2 controls cancer cell survival by modulating gluconeogenesis
mTOR inhibition reduces metabolic flux to the mitochondria. (a–c) Cells were treated/transfected as described earlier and pyruvate, acetyl-coA and citrate levels were measured in triplicate samples in whole-cell lysates and normalized to the total cellular protein as described in Materials and Methods. All panels: n=4, *P<0.05, **P<0.01 compared with Con or sc cells.
