Table 1 Kinetic parameters of P2X7 receptor in CHO cells

From: Post-translational allosteric activation of the P2X7 receptor through glycosaminoglycan chains of CD44 proteoglycans

Agonist

CHO-K1

CHO-745

 

E max (URF)

EC50 (μM)

Hill coefficient

E max (URF)

EC50 (μM)

Hill coefficient

ATP

258±10

3.2±0.3

0.9±0.1

97±7

8±1

2.0±0.3

BzATP

275±8

23±2

1.0±0.1

136±6

21±3

1.8±0.2

BzATP+Mg2+

153±6

168±22

1.5±0.1

119±10

150±11

2.8±0.3

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