Figure 4

Doxorubicin and histamine effects on TBARS levels of H4R−/− mice compared with WT Balb/c mice. TBARS levels were determined in mice (a) heart and (b) liver of WT and KO mice. Data are expressed as nmol/mg of tissue. (8–12 mice per group, *P<0.05 versus WT Control; #P<0.05, ##P<0.01 versus WT Dox).