Figure 1 | Cell Death Discovery

Figure 1

From: p53 Configures the G2/M arrest response of nucleostemin-deficient cells

Figure 1

Loss of p53 decreases the proliferative potential of NS-depleted mouse embryonic fibroblast (MEF) cells. MEF cells were prepared from NSflx/flx or inNScko embryos in the p53-wild-type (p53wt) (a) or p53-null (p53ko) (b) background and treated with 0.1 μM tamoxifen (TAM) or DMSO from passage 1 (P1) to P4–P6. The proliferative potential was determined as the average daily cell expansion ratio during each passage. Bars and error bars represent the average and s.e.m. *P⩽0.01, **P⩽0.001 and ***P⩽0.0001.

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