Figure 4 | Cell Death Discovery

Figure 4

From: Sundew plant, a potential source of anti-inflammatory agents, selectively induces G2/M arrest and apoptosis in MCF-7 cells through upregulation of p53 and Bax/Bcl-2 ratio

Figure 4

In vitro anti-inflammatory effects of DBME in RAW 264.7 cells. (a) Effect of DBME on cell proliferation and viability of murine macrophage RAW 264.7 cells. (b) Effect of DBME on LPS-induced production of nitrite. (c) Effect of DBME on LPS-induced production of TNF-α. (d) Effect of DBME on LPS-induced production of ROS. (e) Effect of DBME on LPS-induced expression of inflammatory proteins. (f) Effect of DBME on LPS-induced mRNA levels of inflammatory proteins in RAW 264.7 cells. Cytotoxicity data are expressed as mean±S.D. (N=6); *P<0.05, **P<0.01 and ***P<0.001 versus 0 μg/ml. Nitrite, TNF-α and ROS data are expressed as mean±S.D. (N=3); *P<0.05, **P<0.01 and ***P<0.001 versus 0 μg/ml LPS. #P<0.05, ##P<0.01 and ###P<0.001 versus 1 μg/ml LPS.

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