Figure 5
From: The plant defensin NaD1 induces tumor cell death via a non-apoptotic, membranolytic process
MM170 cells display a necrotic phenotype following subacute treatment of NaD1 over 24 h. Morphological changes in MM170 cells following treatment with NaD1 (1.25 μM) or ultraviolet (UV) radiation were examined via DIC live cell imaging by spinning disk confocal microscopy. (a) NaD1-treated cells were imaged over 24 h, with images recorded at 0, 6, 16 and 24 h time points. Scale bars in (a) represent 20 μm. (b) MM170 cells exposed to UV radiation were imaged 6 h after exposure. Data are representative of three independent experiments.
