Figure 3 | Cell Death Discovery

Figure 3

From: BUB1 and SURVIVIN proteins are not degraded after a prolonged mitosis and accumulate in the nuclei of HCT116 cells

Figure 3

BUB1 and SURVIVIN protein levels decrease in a similar pattern during a prolonged mitosis in HCT116 and HT29 cells. Western blot analysis of paclitaxel-treated HCT116 (a) and HT29 (b) cells after thymidine block. In both HCT116 and HT29 cell lines, BUB1 and SURVIVIN levels diminish over time, whereas the levels of the mitotic checkpoint protein MAD2 remain constant during mitotic arrest.

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