Figure 2
From: Development of a lytic peptide derived from BH3-only proteins
Amphiphilicity and positive charge are required for cell-killing properties of ABH3 peptides. (a) CD spectra of ABH3um, ABH3 and ABH3E. CD spectral measurements were performed in PBS buffer, 10 mM, pH 7.4, 298 K; (b) Cell viability of HCT116 cell lines after treatment with ABH3um, ABH3 and ABH3E (24 h); (c) Cellular uptake of ABH3um FITC, ABH3FITC and ABH3E FITC, (1 h). Values are expressed as mean (±S.D.) (n=3).
