Figure 4
From: Development of a lytic peptide derived from BH3-only proteins
ABH3 induced cell membrane destruction. (a) LDH release of HCT116 following treatment of ABH3 or ABT-737 (20 μM, 4 h); (b) PI staining of U937 cells following treatment with ABH3 and ABT-737 (10 μM, 0.5 h); (c) Scanning electron microscope image of HCT116 upon treatment with ABH3 (10 μM, 1 h), (i) control, (ii) treated by ABH3. Values are expressed as mean (±S.D.) (n=3).
