Table 3 Risk of death in lung squamous cell carcinoma patients according to FLIP and procaspase-8 expression within the nucleus and cytoplasm in tumor and stromal compartments
Alive, n=37 (%) | Dead, n=52 (%) | Unadjusted hazard ratios (95% confidence intervals) | Adjusted a hazard ratios (95% confidence intervals) | |
|---|---|---|---|---|
Tumoral FLIP nucleus | ||||
Low (⩽92) | 7 (18.9) | 19 (36.5) | 1.00 | 1.00 |
High (>92) | 30 (81.1) | 33 (63.5) | 0.70 (0.40–1.23) | 0.66 (0.36–1.23) |
Tumoral FLIP cytoplasm | ||||
Low (⩽231) | 28 (75.7) | 28 (53.9) | 1.00 | 1.00 |
High (>231) | 9 (24.3) | 24 (46.2) | 1.62 (0.94–2.81) | 1.31 (0.70–2.44) |
Stromal FLIP nucleus | ||||
Low (⩽86.5) | 22 (59.5) | 41 (78.9) | 1.00 | 1.00 |
High (>86.5) | 15 (40.5) | 11 (21.2) | 0.55 (0.28–1.06) | 0.52 (0.25–1.10) |
Stromal FLIP cytoplasm | ||||
Low (⩽127.5) | 18 (48.7) | 17 (32.7) | 1.00 | 1.00 |
High (>127.5) | 19 (51.4) | 35 (67.3) | 1.41 (0.79–2.51) | 1.08 (0.57–2.05) |
Tumoral procaspase-8 nucleus | ||||
Low (⩽59.5) | 8 (21.6) | 17 (32.7) | 1.00 | 1.00 |
High (>59.5) | 29 (78.4) | 35 (67.3) | 0.77 (0.43–1.38) | 0.73 (0.37–1.44) |
Tumoral procaspase-8 cytoplasm | ||||
Low (⩽147.5) | 10 (27.0) | 21 (40.4) | 1.00 | 1.00 |
High (>147.5) | 27 (73.0) | 31 (59.6) | 0.87 (0.50–1.52) | 0.84 (0.45–1.55) |
Stromal procaspase-8 nucleus | ||||
Low (⩽36.5) | 16 (43.2) | 16 (30.8) | 1.00 | 1.00 |
High (>36.5) | 21 (56.8) | 36 (69.2) | 1.49 (0.83–2.70) | 1.64 (0.87–3.09) |
Stromal procaspase-8 cytoplasm | ||||
Low (⩽88.5) | 11 (29.7) | 19 (36.5) | 1.00 | 1.00 |
High (>88.5) | 26 (70.3) | 33 (63.5) | 0.98 (0.56–1.73) | 1.16 (0.59–2.28) |
