Table 3 SCRIB proteomic analysis in the absence and presence of ADRA1D
From: Individual protomers of a G protein-coupled receptor dimer integrate distinct functional modules
EXP | SCRIB | SCRIB interactors | ADRA1D interactors | |||||
|---|---|---|---|---|---|---|---|---|
TAP-SCRIB | %Cov | #UP | Name | %Cov | #UP | Name | %Cov | #UP |
+ Empty vector | 58.1 | 137 | ARHGEF6 | 5.5 | 11 | a | a | a |
ARHGEF7 | 19.8 | 7 | ||||||
GIT1 | 13.5 | 6 | ||||||
PPP1CC | 31.8 | 2 | ||||||
+ ADRA1D | 59.1 | 134 | ARHGEF6 | 18.3 | 8 | ADRA1D | 26.2 | 6 |
ARHGEF7 | 24.3 | 11 | DTNA | 3.5 | 1 | |||
GIT1 | 42.6 | 24 | SNTB2 | 4.9 | 1 | |||
PPP1CC | 18.5 | 5 | UTRN | 1.3 | 4 | |||
+ ADRA1D–ΔPDZ | 57.8 | 137 | ARHGEF6 | 18 | 6 | a | a | a |
ARHGEF7 | 23.7 | 11 | ||||||
GIT1 | 36.9 | 21 | ||||||
PPP1CC | 18.5 | 5 | ||||||
