Table 4 Multimeric ADRA1D proteomic analysis

From: Individual protomers of a G protein-coupled receptor dimer integrate distinct functional modules

EXP

ADRA1D

PDZ proteins

Non-PDZ proteins

 

%Cov

#UP

Name

%Cov

#UP

Name

%Cov

#UP

TAP–ADRA1D

15.4

9

SCRIB

10.7

12

CTNNAL1

1.1

1

   

SNTB1

27.9

11

DMD

3

10

   

SNTB2

42.4

19

DTNA

17.6

5

      

UTRN

17

50

TAP−ADRA1D–ΔPDZ

12.8

3

a

a

a

a

a

a

TAP−ADRA1D–ΔPDZ

17.8

10

SCRIB

a

a

CTNNAL1

a

a

+ Myc–ADRA1D

  

SNTB1

12.8

4

DMD

8.4

3

   

SNTB2

37

16

DTNA

14.4

2

      

UTRN

8.8

21

  1. HEK293T cell lysates expressing WT (TAP–ADRA1D), ΔPDZ (TAP–ADRA1D–ΔPDZ) α1D-AR, or TAP–ADRA1D–ΔPDZ co-transfected with MYC α1D-AR (Myc–ADRA1D) were subjected to TAP/MS. Shown are % protein coverage (%Cov), number of unique peptides (#UP) for PDZ and non-PDZ proteins.
  2. aNo proteins detected.
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