Figure 5 | Cell Discovery

Figure 5

From: eIF2 interactions with initiator tRNA and eIF2B are regulated by post-translational modifications and conformational dynamics

Figure 5

Location of post-translational modifications (PTMs) in eukaryotic initiation factor 2B (eIF2B). Phosphosites and acetylation sites identified in this or previous studies are shown on the protein subunits of eIF2. The proteins are represented as bars. The arrows represent the parts of the sequences for which homology models could be obtained. The magnification shows a phosphosite cluster of eIF2Bε. This cluster is located in a flexible loop connecting the ε/γ dimer (cartoon insert) and the catalytic domain of eIF2Bε.

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