Figure 6
From: Increased dysbindin-1B isoform expression in schizophrenia and its propensity in aggresome formation
Inhibitory effect of dysbindin-1B on neurite outgrowth in cortical neurons. (A) Representative images of cortical neurons were obtained from wild-type E15.5 mice 48 h following transfection with GFP and GFP-tagged dysbindin-1B. (B) The relative average length of the longest neurites in neurons from wild-type mice expressing GFP and GFP-tagged dysbindin-1B. The GFP control was treated as 100%. (C) The relative average length of the longest neurites in neurons from sandy mice expressing GFP and GFP-tagged dysbindin-1B. The GFP control was treated as 100%. Data were collected from 3 independent experiments and presented as mean±s.e.m. ***P<0.001. ns, not significant. Scale bar, 20 μm. GFP, green fluorescent protein.
