Figure 3
From: Discovery of a highly potent glucocorticoid for asthma treatment
Examination of the efficacy of VSGC12 in a mouse OVA-induced asthma model. (a) Lung function (AHR) of BALB/c mice with different treatment. RL, resistance of lung, cm H2O.s/ml. ACH, acetylcholine. (b) Differentiated cells count. Macro, macrophage; Eos, eosinophils; LC, lymphocytes; PMN, phagocytic monocytes. (c) OVA-specific IgE. OD, arbitrary unit=(OD405–OD540)×dilution factor. (d) Histology score, left panel, hematoxylin and eosin (HE) staining; right panel, PAS staining. Error bars indicate s.e.m., each group n=10. *P<0.05; **P<0.01; ***P<0.001; n.s., not significant.
