Figure 3 | Cell Discovery

Figure 3

From: The interchange of immunophilins leads to parallel pathways and different intermediates in the assembly of Hsp90 glucocorticoid receptor complexes

Figure 3

Formation of the hexameric client complex. (a) Incubation of stoichiometric ratios (all at 0.5 μm) of (Hsp70)2, GR, Hop and (Hsp90)2 in the presence of Hsp40 leads to the formation of a hexameric client-transfer complex as reported previously [18]. (b) On addition of an equimolar ratio of FKBP52 to this complex binding of a single FKBP52 subunit is observed (charge states labelled blue).

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