Figure 4
Set1 binding to RNA occurs via two different modes and requires its dRRM. (a) Dispersion plot showing high correlation between the Set1 and RNAPII CRAC signals. The determination coefficient (r2) of the linear, least squares regression is indicated. (b) Dispersion plot of Set1 CRAC signals versus Set1 ChIP-Seq (IP/input). (c) Distribution of the Set1 CRAC/Set1 ChIP ratios for all mRNAs coding genes. The average, mode and median are indicated to highlight the asymmetry of the distribution. The shaded area corresponds to the percentage of features whose Set1 CRAC/ChIP ratios are included in a range symmetrically positioned around the mode. (d) Distribution of the Set1/RNAPII CRAC ratios in cells expressing PTH-Set1 and PTH-Set1YF/AA.
