Figure 4 | Cancer Gene Therapy

Figure 4

From: Highly potent and specific siRNAs against E6 or E7 genes of HPV16- or HPV18-infected cervical cancers

Figure 4

Colony formation was inhibited in HPV-positive cervical cancer cells by HPV-siRNAs. A total of 1000 cells (Caski or HeLa or C33A) transfected with a specific HPV-siRNA plasmid were seeded in six-well plates and allowed to grow for 10 days. The identity of each HPV-siRNA is indicated at the top of each plate. Relative levels of colony formation were quantified and are shown below each plate. (a) Suppression of colony formation by HPV-16-siRNAs in Caski cells. (b) Suppression of colony formation by HPV-18-siRNAs in Caski cells. (c) Minimal effect of colony formation by HPV-siRNAs in non-HPV infected C33A cells.

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