Figure 6
In vivo visualization of virally infected cell delivery in the presence of anti-herpes simplex virus type 1 (HSV-1) antiserum. Mice were bearing disseminated SKOV3 ovarian tumors. Mice were randomized into non-treatment group (a, b) and treatment group with anti-HSV-1 antiserum (c, d). Intraperitoneal tumor-bearing mice were given phosphate-buffered saline (PBS) (a), cell-free HF-green fluorescent protein (GFP) (b, c) or HF-GFP-infected human omentum mesothelial cells (HomMCs) (d) intraperitoneally 1 h after treatment. Representative photographs showing between tumor location and GFP signal. Each picture taken 24 h after viral injections is shown. The yellow arrows and dotted-line circles indicate disseminated ovarian tumor.
