Figure 2 | Cancer Gene Therapy

Figure 2

From: Chemovirotherapy for head and neck squamous cell carcinoma with EGFR-targeted and CD/UPRT-armed oncolytic measles virus

Figure 2

Targeting specificity of MV-EGFP-antiEGFR. (a) Mean fluorescence intensity of the surface marker EGFR was determined via FACS analyses of HNO97 (continuous line), HNO210 (dotted), HNO410 (broken) and MCF-7 as control (gray marked). (b) Three HNSCC cell lines, MCF-7, HT1080-CD20 and Vero-αHis cells were infected with the respective viruses (indicated above of each row) at a MOI of 1. Pictures were taken at 48 h p.i. using a fluorescence microscope ( × 100 magnification). Merged pictures of EGFP fluorescence and phase contrast are shown.

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