Table 1 GFI1B expression in K562, primary CML cells and hematopoietic progenitor cells measured by real-time RT-PCR
Disease | GFI1B expression (%) | P-value compared with healthy volunteers CD34+ cells |
---|---|---|
K562 (n=18) | 218.4±96.7 | <0.01 |
CML in first chronic phase (n=10) | 36.7±13.6 | <0.01 |
CML in advanced phase (n=4) | 58.2±13.5 | <0.01 |
CML in blastic crisis (n=4) | 122.9±52.1 | <0.04 |
Healthy volunteers | ||
CD34+ cells (n=2) | 1.65±0.35 | − |
CD34− cells | 0.16±0.01 | NS |