Figure 2 | Cellular & Molecular Immunology

Figure 2

From: Differences in phenotype, homing properties and suppressive activities of regulatory T cells induced by epicutaneous, oral or sublingual immunotherapy in mice sensitized to peanut

Figure 2

Immunotherapies induced the desensitization of peanut-sensitized mice. Sensitized mice were EPIT-, OIT-, SLIT- or sham-treated for 8 weeks. The quantities of peanut-specific IgE (a) and IgG2a (b) were measured for each group and before treatment after sensitization (before) and after the treatment period (after). The production of Th2 cytokines (IL-5 and IL-13) (c) and IL-10 and IFN-γ (d) were measured after in vitro stimulation with peanuts for 72 h. Cytokine levels were measured using Bioplex. The data are shown as the median with range from three independent experiments with n=8 for each group of mice. *P<0.05; **P<0.01; ***P<0.001; #P<0.05 compared with EPIT.

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