Figure 5
Sex chromosome evolutionary features and DMRT1 splice variants. (A) Human X and chicken Z chromosome assignments of genes orthologous to the Chinese alligator gonadal differentially expressed genes (DEGs). (B) Expression profiles of DEGs orthologous to X chromosome-located genes. (C) Expression profiles of DEGs orthologous to Z chromosome-located genes. (D) Multi-color fluorescence in situ hybridization (M-FISH) analysis of DMRT1 and other representative genes in males. (E) M-FISH analysis in females. (F) Syntenic relationship between alligator chromosome 3 and chicken chromosome Z. Sex-related genes were selected from synteny comparison results (Supplementary information, Figure S14). (G) Genomic structure of the Chinese alligator DMRT1 splice variants and their expression profiles in male and female gonads.
