Figure 1 | Cell Research

Figure 1

From: Structural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone

Figure 1

Structure of the PP2A-PTPA-ATPĪ³S complex. (A) Overall structure of the PP2A-PTPA-ATPĪ³S complex. Mini-A, PP2Ac and PTPA are shown in ribbon and colored green, blue and orange, respectively. (B) A slice of surface showing the combined ATP-binding pocket bound to ATPĪ³S (left) and its electrostatic potential (right). The 2Fo-Fc electron density for ATPĪ³S at 1.5Ļƒ is shown in magenta. The color scheme is the same as in A. For all panels, ATPĪ³S is in cylinder and colored by atom type. PP2A catalytic metal ions are indicated by spheres.

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