Figure 2 | Cell Research

Figure 2

From: Postzygotic single-nucleotide mosaicisms in whole-genome sequences of clinically unremarkable individuals

Figure 2

Specificity and precision of identifying pSNMs using our pipeline, Varscan 2, and muTect. (A-B) False positive rate for true reference sites (A) and true non-reference sites (B). Error bars: 95% confidence intervals. (C) Proportion of true pSNMs among all identified sites. The postzygotic mutation rate was set to 4.4 × 10−7 per base, based on estimates in this study. The X axis denotes the minor allele fraction of the pSNM sites.

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