Figure 6
From: Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z
Anp32e disrupts non-nucleosomal aggregates formed by DNA and H2A.Z-H2B dimers. H2A.Z-H2B or H2A-H2B dimers were mixed with 601 sequence DNA to form aggregates. One- to three-fold molar ratios of recombinant Anp32e, NAP1 or Anp32a were then titrated into the aggregates to examine their chaperone activity in dissolving non-nucleosomal DNA-histone aggregates. (A) H2A.Z. (B) H2A.
