Figure 6

Development of HCC classifiers. (A, B) For classifier I, the classifier scores of HCC patients, cirrhosis patients and normal individuals (A) and AUC curves (B) are shown. The dash line in A indicates the cutoff at 0.5. (C, D) For classifier II, the number of hypermethylated markers (C) and AUC curve (B) are shown. The dash line in C indicates the cutoff at 5.5. The green arrow in D indicates the point nearest the upper left corner of the ROC curve that gives the cutoff. Black: the training group; red: the testing group.