Figure 1 | Cell Research

Figure 1

From: Detecting hepatocellular carcinoma in blood

Figure 1

Hypermethylated cfDNA released into the blood can be detected with a new method. Cell-free DNA-containing hypermethylated CpG islands (mCGIs) circulating in the blood of heptocellular carcinoma patients can be detected for early diagnosis. These marker DNAs are released by either tumor cells undergoing apoptosis or necrosis (type I) or adjacent non-cancerous cells affected by tumor growth (type II).

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