Figure 3 | Cell Research

Figure 3

From: Vertical transmission of Zika virus targeting the radial glial cells affects cortex development of offspring mice

Figure 3

Effects of ZIKV infection on gene expression. (A) Quantitative real-time PCR analysis of the mRNA levels of cell cycle-related and microcephaly-related genes in ZIKV-injected E17.5 fetal brains. GAPDH was used as the internal control. Data are mean ± SEM from 3 experiments (*P< 0.05, **P< 0.01, ***P< 0.001, NS, no significant difference, Student's t-test). (B, C) RNA-seq and GO analyses reveal pathways that are significantly up-regulated (B) and significantly down-regulated (C) in ZIKV-injected E17.5 fetal brains compared with control samples. Bar plots show the –log10 P values of each term of genes.

Back to article page