Figure 1 | Cell Research

Figure 1

From: Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types

Figure 1

(A) Comparison of IgG Gal-ratio values of serum samples obtained from non-cancer controls and cancer patients in the validation cohort. (B) ROC curve for IgG Gal-ratio to distinguish cancer patients from non-cancer controls in the validation cohort. (C) Performance of IgG Gal-ratio in the detection of individual cancer types in the validation cohort. (D) Performance of IgG Gal-ratio and classical biomarkers for the diagnosis of gastric, liver, lung, ovarian, colorectal, esophageal, pancreatic and prostate cancers in the validation cohort. (E) The positive rates of IgG Gal-ratio marker and classical biomarkers in cancer patients, and the Gal-ratio positive rates in patients with different classical biomarker statuses in the validation cohort. (F) ROC curve for IgG Gal-ratio to distinguish patients with early-stage cancers from non-cancer controls in the validation cohort. (G) Comparison of Gal-ratio values in serum samples obtained from patients with ovarian cancer and those with inflammatory gynecological diseases (a). ROC curve for IgG Gal-ratio to distinguish patients with ovarian cancer from those with inflammatory gynecological diseases (b).

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