Figure 3
From: 5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages
Cell-free 5hmC for monitoring HCC progression and treatment. (A) tSNE plot of 5hmC FPKM from healthy, HBV and HCC samples. (B) Heatmap of 1 006 HCC differential genes in healthy, HBV and HCC samples. Hierarchical clustering was performed across genes and samples. (C, D) Boxplots of AHSG (C) and TET2 (D) 5hmC FPKM in HBV, HCC (pre-op), HCC post-op, HCC recurrence and other cfDNA samples. *P < 0.05, **P < 1e-4, ***P < 1e-5, Welch t-test. (E) tSNE plot of 5hmC FPKM from healthy, HCC pre-op, HCC post-op and HCC recurrence samples.
