Figure 6
From: De novo DNA methylation during monkey pre-implantation embryogenesis
dnmt3a and dnmt3b knockdown improves developmental potential of the embryos. (A) Morpholinos can significantly knock down endogenous dnmt3a and dnmt3b expression in monkey embryos (n = 3, * represents P ≤ 0.05). (B) Bar graph showing percentages of embryos that reach the blastocyst stage after injection of dnmt3a and dnmt3b morpholinos or negative control morpholino (Three independent experiments. Totally 15 embryos were used in control and knockdown experiments, respectively. Error bars represent SD. * represents P ≤ 0.05).
