When Ira Mellman joined Genentech in 2007, the cancer immunotherapy revolution had not yet begun. Only in 2008 did Medarex unveil the first phase I data from its PD1 blocker MDX-1106, later to become Bristol Myers Squibb’s nivolumab (Opdivo). As follow-up data started hinting at profound and lasting therapeutic effects for these agents, everyone piled in and the race began.
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Interviewed by Asher Mullard
The interview was edited for length and clarity.