Table 3 Primary and secondary outcomes

From: Use of a fermented dairy probiotic drink containing Lactobacillus casei (DN-114 001) to decrease the rate of illness in kids: the DRINK study A patient-oriented, double-blind, cluster-randomized, placebo-controlled, clinical trial

 

Active Least squares mean (s.e.)

Control Least squares mean (s.e.)

P-value

Primary outcomes

   

 Incidence rate of CID per 100 person daya

7.8 (0.4)

9.8 (0.7)

0.046

 Rate of days with change in activity because of illness per 100 person dayb

2.30 (0.21)

2.27 (0.21)

0.91

Secondary outcomes

   

 Incidence rate of GITI per 100 person daya

1.2 (0.10)

1.6 (0.15)

0.042

 Incidence rate of URTI per 100 person daya

2.7 (0.18)

3.3 (0.20)

0.036

 Incidence rate of LRTI per 100 person daya

2.7 (0.16)

2.8 (0.18)

0.829

 Rate of vomiting per 100 person day

0.55 (0.08)

0.73 (0.08)

0.10

 Rate of stomach pain per 100 person day

1.23 (0.21)

1.50 (0.21)

0.36

 Rate of constipation per 100 person day

0.81 (0.18)

0.71 (0.18)

0.68

 Rate of runny nose per 100 person day

7.88 (0.63)

8.65 (0.63)

0.39

 Rate of cough per 100 person day

9.18 (0.63)

8.37 (0.63)

0.36

 Rate of decreasing appetite per 100 person day

2.58 (0.31)

2.31 (0.31)

0.54

 Rate of fever per 100 person day

1.34 (0.14)

1.34 (0.14)

0.99

 Rate of rash per 100 person day

1.17 (0.23)

0.76 (0.23)

0.21

  1. Abbreviations: CID, common infectious disease; GITI, gastrointestinal tract infections; LRTI, lower respiratory tract infections; URTI, upper respiratory tract infections.
  2. aIncidence rate per 100 person day=incidence rate per day × 100.
  3. bRate of days with change in activity because of illness=number of days with change in activity/number of days in the study.
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