Table 2 Total and individual scores of gastrointestinal symptoms in the 24 and 48 h following consumption of dairy desserts containing 35 g dextrose (control dessert) or different mixtures of maltitol and scFOS in the ITT population (n=36)

From: Digestive tolerance and postprandial glycaemic and insulinaemic responses after consumption of dairy desserts containing maltitol and fructo-oligosaccharides in adults

  

Control

Dextrose 24 scFOS 11

Maltitol 35

Maltitol 30 scFOS 5

Maltitol 24 scFOS 11

Maltitol 17.5 scFOS 17.5

Dessert effect (P-value)

0–24 h

Total score

3.15±4.26a

6.46±5.85b

8.86±6.49b,c

8.53±7.10b,c

9.41±6.99b,c

10.80±7.98b,c

<0.0001

 

Flatulence

1.21±1.49

2.11±2.26

3.37±2.56*

2.74±2.50*

3.68±2.46*

4.11±2.34*

<0.0001

 

Borborygmi

0.70±1.31

1.49±2.01

2.11±2.40*

2.41±2.43*

1.85±2.30*

2.43±2.40*

<0.0001

 

Bloating

0.70±1.69

1.40±2.20

1.60±2.24

1.74±2.15

1.82±2.41

2.17±2.72*

0.0312

 

Discomfort

0.55±1.68

1.46±2.41

1.77±2.44*

1.65±2.98

2.06±2.95*

2.09±2.70*

0.0135

24–48 h

Total score

0.88±1.71a

2.34±3.55a,b

3.60±5.39b

2.62±3.57b

2.24±3.37a,b

2.71±4.26b

0.0063

 

Flatulence

0.27±0.80

0.83±1.50

1.37±1.99*

1.12±1.61*

1.06±1.54*

1.20±1.78*

0.0037

 

Borborygmi

0.30±0.81

0.31±0.93

0.74±1.60

0.79±1.49

0.44±1.13

0.57±1.29

0.0823

 

Bloating

0.12±0.55

0.49±1.17

0.69±1.64

0.35±0.92

0.47±1.02

0.57±1.36

0.2084

 

Discomfort

0.18±0.58

0.71±1.54

0.80±1.64*

0.35±1.01

0.26±0.79

0.37±1.19

0.0448

  1. Abbreviations: ITT, intention to treat; scFOS, short-chain fructo-oligosaccharides.
  2. Each symptom is scored between 1 and 10; data is expressed in arbitrary unit mean±s.d.
  3. a,b,cDesserts not sharing the same letter are significantly different (P<0.05, Dunnett’s post hoc test vs the Control or Tukey’s test among the five other mixtures).
  4. *Significant increase (Dunnett’s test) in gastrointestinal symptom scores compared with 35 g dextrose, P<0.05. Other observed differences (Tukey’s test) for flatulence at 24 h: maltitol 24–scFOS 11 vs scFOS 11 (P=0.0197); maltitol 17.5–scFOS 17.5 vs scFOS 11 (P=0.0005); maltitol 17.5–scFOS 17.5 vs maltitol 30–scFOS 5 (P=0.0377).