Table 2 Densities of serotonin- and PYY-immunoreactive cells in the total colon, right colon and left colon of control subjects and of IBS patients before and after receiving dietary guidance

From: Dietary guidance normalizes large intestinal endocrine cell densities in patients with irritable bowel syndrome

Hormone/location

Cell density (cells/mm2)

 

Control

Before guidance

After guidance

P-value

Serotonin

 Total colon

46.8±8.9

10.5±2.1

22.6±3.2

0.007b

 Right colon

25.9±5.4

1.2±0.8

10.7±1.6

<0.0001c

 Left colon

20.9±4.8

8.9±1.7

10.6±1.9

0.53

PYY

 Total colon

11.6± 1.8

10.8±1.7

16.8±2.1

0.06

 Right colon

3.9±0.8

2.9±0.8

5.5±1.1

0.1

 Left colon

7.7±1.4

7.9±1.0

11.5±1.1

0.04a

  1. Abbreviations: IBS, irritable bowel syndrome; PYY, peptide YY.
  2. Data are presented as mean±s.e.m.
  3. aP<0.05, bP<0.01 and cP<0.0001.
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