Table 2a Hb, ferritin, TIBC, TfR and CRP concentrations among healthy infant and lactating mother in Bhaktapur, Nepal

Indicators	Infant (2–12 months)	Mother (15–44 years)^a	Spearman's correlation (P-value)^b
Hb, n	474	500
Mean, s.d. (g/dl)	10.7 (1.3)	13.1 (1.3)	0.16 (0.01)
Anemia adjusted for altitude^c	69	20
Mild anemia (%)^c	34	17
Moderate anemia	35	3
Severe anemia	0.4	0
Ferritin, n	448	500
Mean (s.d.) (μg/l)	54.8 (69.8)	68.8 (45.9)	0.12 (0.01)
Depleted iron stores^d	20	5
Iron deficiency anemia^d	17	4
TIBC, n	448	500
Mean (s.d.) (μmol/l)	72.6 (12.1)	72.7 (10.7)	0.09 (0.04)
High TIBC >83 μmol/l	18	15
TfR, n	449	500
Mean (s.d.) (mg/l)	6.2 (3.1)	3.4 (1.5)	0.21 (<0.001)
Iron-deficient erythropoeisis^e	76	16
Iron-deficient erythropoeisis and anemia	20	6
CRP, n	448	500
Mean (s.d.) (mg/l)	4.3 (10.8)	1.8 (6.5)
> 5 mg/l	21	5
Ratio TfR/log ferritin, mean (s.d.) ^f	2.3 (3.1)	0.95 (0.88)
>2	38	5
TfR/ferritin index, mean (s.d.) ^f	499 (1142)	110 (289)
>500	22	3

Abbreviations: CRP, C-reactive protein; Hb, hemoglobin; TfR, plasma transferrin receptor; TIBC, total iron-binding capacity.
^aAll values are in %, unless specified otherwise.
^bSpearman's correlation coefficient between mother and their infant iron parameters.
^cThe cutoffs for altitude-adjusted anemia, mild, moderate and severe were <12.3 , 10.3–12.2, 7.3–10.2 and <7.3 g/dl among mothers and <11.3, 9.3–11.2, 7.3–9.2 and <7.3 g/dl among infants.
^dDepleted iron store was defined as ferritin <15 μg/l among mothers and <12 μg/l for infants. Iron deficiency anemia was considered when depleted iron stores were combined with Hb <12.3 g/dl among mothers and <11.3 g/dl among infants.
^eIron-deficient erythropoesis was defined TfR values of >4.4 mg/l.
^fThe TfR-log ferritin ratio was calculated by dividing TfR with the log transformation of plasma ferritin, and the TfR-ferritin index was calculated by dividing TfR and ferritin concentrations in microgram unit.

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