Table 1 Allele frequencies in the African populations in this study and other ethnicities or populations

	CYP2C19		CYP2D6								NAT2				GST		CYP2B6
Population	*2	*3	*2/2	*3	*4	*5	*10	*9	*17	*29	*5	*6	*7	*14	M1 del/del	T1 del/del	*6
Orientals	30	10	2	0	1	6	51	0	0	0	5	25	13	0	55	65	18
Chinese	37	8	1	0	1	6	51	0	0	0	6	31	16	0	58	53	21
Japanese	35	11	1	0	1	3	43	0	0	0	2	19	10	0	44	44	16
Koreans	21	12	0	0	2	6	51	0	0	0	3	19	11	0	53	60	15
Caucasian	15	0	5	2	25	5	2	2	0	0	49	27	2	0	50	15	21
Swedes	17	0	1	3	23	5	1	0	0	0	51	28	2	0	51	20
Germans	18	0	2	2	20	2	2	0	0	0	46	27	4	0	51	21
American	14	0	2						0		45	28	2	0	54	15
Mixed African	16	1	2	<1³	2	4	6	0	30	15	34	20	5	13	30		40
African American	25	0	1	<1³	7	6	4	1	15	5	30	22	2	9	28	24	47
Tanzanian	18	<1 ³	3	0	2	4	4	0	18	20	34	21	3	13	33	25	39
Shona	13	^b	2	0	2	4	6	0	34	17	31	21	6	14	24	26	38
Venda	21	0		0	3	5	12	0	24	6	39	22	5	11	23	20	36
Ghanaian			2	0	7	6	3	0	28	—	—	—	—	—	39	—	49
Ethiopians	14	2	15	0	4	3	9	0	9	—	—	—	—	—	—	—	—
Kikuyu	16	0		0	1			0	33	14	58	24			28	25	34
Luo	18	0		0	4		6	0	23	16	34	22	3	14	29	22	37
Maasai	11	<1 ³		0	8		5	0	18	8	42	27	4	9	16	40	35
Igbo	29	0		0	8		10	0	14	20	28	29	4	11	23	36	38
Yoruba	10	0		0	3		7	0	22	10	33	27	3	8	31	35	42
Hausa	12	0		0	2		13	0	18	10	27	33	3	3	37	42	42
San	12				9			0	22	2	20	8			45		40

Abbreviation: glutathione-S-transferase.
The numbers in bold are frequencies obtained in this study, the nonbold are literature data compilations.³ Fifteen SNPs/polymorphisms were analyzed and compared to literature data. The CYP2D6 polymorphisms (^*5 and ^*2/2) were not analyzed in this study, but were included in the stratification analysis. The exact description of the CYP alleles can be found on www.imm.ki.se/CYPalleles.
The frequency of the allele is rare (>1%), a few individuals have been described but constitute a rare occurrence.
Where frequency is 0, so far the allele has not been found in the individuals studied in the respective population.

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