Figure 3
From: Study of smell and reproductive organs in a mouse model for CHARGE syndrome
Macroscopic and microscopic analysis of olfactory bulbs from wild-type and Chd7Whi/+ mice. (a–c) Macroscopic view of brains of adult wild-type and Chd7Whi/+ mice, with the olfactory bulb/brain length ratio measured as mean olfactory bulb length divided by length of cerebral hemispheres (arrows in a). (b) Left olfactory bulb consisting of two parts, (c) asymmetrical olfactory bulb hypoplasia. (d, e) Nissl-stained coronal sections of adult wild-type and Chd7Whi/+ olfactory bulbs, showing no abnormalities. (f) Scatter plot of the olfactory bulb/brain length ratio of adult wild-type and Chd7Whi/+ mice. Scale bars=5 mm (a–c); 100 μm (d and e). gl, glomerular cell layer; ml, mitral cell layer; and pgl, periglomerular layer.
