Figure 1 | European Journal of Human Genetics

Figure 1

From: Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women

Figure 1

Diagrammatic representation of the protein structure of the P2X7R. The positions of amino acid changes as a result of the five polymorphisms included in this study are shown on the diagram. The three C-terminal and one ATP-binding site polymorphisms confer LOF (circles) while His155Tyr gives a weak GOF (triangle). The sixth polymorphism is located in intron 1.

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