Figure 1

Simulated power by different levels of correlation between visits ρ (top) with effect size β fixed at 0.20, and simulated power by different levels of effect size β (bottom), with ρ fixed at 0.20. Power was simulated for single visit, Average and SHAVE. In both plots, alpha level was set to 5 × 10−8 and minor allele frequency at 0.5.