Table 2 Association results between 14 traits and their corresponding top SNPs, where top SNPs were selected based on visit 1 results of SardiNIA GWAS, and where z-statistics for Average and SHAVE are based on three visits

From: SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits

TRAIT

SNP

z1

z2

z AVG

z SHAVE

Visit 1

Visit 2

Average

SHAVE

Bilirubin

rs887829

27.33

27.37

31.44

31.59

4

3

2

1

Cholesterol

rs4910742

−6.25

−4.96

−5.88

−6.04

1

4

3

2

γ-GT

rs7310409

−6.29

−6.52

−6.53

−6.69

4

3

2

1

Glycemia

rs853787

−7.17

−7.50

−8.06

−8.24

4

3

2

1

HDL

rs247617

8.45

8.93

10.10

10.19

4

3

2

1

Height

rs3132468

5.91

5.82

5.91

5.92

3

4

2

1

LDL

rs445925

−5.89

−6.13

−6.74

−6.77

4

3

2

1

PR-interval

rs6800541

6.56

5.92

7.10

7.11

3

4

2

1

QT-interval

rs12036340

6.27

5.31

7.21

7.27

3

4

2

1

RBC

rs4910742

23.39

22.19

24.16

24.26

3

4

2

1

Serum iron

rs4820268

8.77

7.52

10.43

10.66

3

4

2

1

Transferrin

rs4854761

9.58

13.04

14.96

15.40

4

3

2

1

Triglycerides

rs10401969

−6.15

−4.72

−6.67

−6.76

3

4

2

1

Uric acid

rs13145758

−11.84

−12.52

−13.80

−14.05

4

3

2

1

Average rank

3.36

3.50

2.07

1.07

  1. The z-statistics are shown in order for visit 1 (z1), visit 2 (z2), Average (zAVG) and SHAVE (zSHAVE). In the next four columns their corresponding ranks within each trait are shown, where 1 is assigned to the most significant and 4 to the least. On the last row, we have the averages of the ranks for each metric.
Back to article page