Table 2 Associations between APOE and cognitive ability adjusted for age and sex

	Logical memory			Verbal fluency test			Digit symbol test			Mill Hill vocabulary scale
	Beta	SE	P	Beta	SE	P	Beta	SE	P	Beta	SE	P
e4 (additive)	−0.027	0.015	0.067	0.055	0.015	<0.001	−0.014	0.013	0.288	0.036	0.014	0.011
e4 (yes vs no)	−0.020	0.017	0.238	0.062	0.017	<0.001	−0.011	0.015	0.457	0.044	0.016	0.006
e2e2	−0.028	0.093	0.914	−0.024	0.094	0.745	−0.057	0.082	0.428	−0.029	0.088	0.633
e2e3	−0.039	0.023	0.181	−0.018	0.024	0.142	0.035	0.021	0.066	0.002	0.022	0.583
e2e4	−0.044	0.049	0.495	−0.025	0.050	0.294	−0.020	0.043	0.689	0.056	0.046	0.399
e3e4	−0.015	0.018	0.664	0.064	0.018	0.001	−0.0002	0.016	0.854	0.044	0.017	0.015
e3e3	—	—	—	—	—	—	—	—	—	—	—	—
e4e4	−0.123	0.046	0.007	0.092	0.047	0.050	−0.048	0.041	0.233	0.036	0.044	0.405

Abbreviations: Beta, standardised beta; P, incremental P-value; SE, standard error. P-values <0.05 are highlighted in bold.

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