Figure 7 | Experimental & Molecular Medicine

Figure 7

From: T-CAM, a fastatin-FIII 9-10 fusion protein, potently enhances anti-angiogenic and anti-tumor activity via αvβ3 and α5β1 integrins

Figure 7

T-CAM inhibits endothelial cell proliferation and induces apoptosis. HUVECs after serum-starvation were incubated in the presence of protein (fastatin, FIII 9-10 or T-CAM) in dose-dependent manner. Cell proliferation was quantified by the MTT assay (A). The induction of apoptosis by either of these proteins were examined by FITC-annexinV staining and FACS analysis (B). *P < 0.05; **P < 0.01 versus untreated control.

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