Figure 4 | Experimental & Molecular Medicine

Figure 4

From: Cross talk between P2 purinergic receptors modulates extracellular ATP-mediated interleukin-10 production in rat microglial cells

Figure 4

Effects of the P2 receptor antagonist on the release of IL-10 from microglial cells. Microglial cells (3 × 104 cells/well) were pretreated with TNP-ATP, MRS2179, 2-meSAMP, oATP, or 5'-AMPS for 30 min at the indicated concentrations, then treated with ATP-γ-S (100 µM), 2-meSADP (100 µM), and BzATP (100 or 300 µM). The amount of IL-10 was measured 24 h after treatment. Data shown are mean ± SEM of triplicate samples. The figure shows one representative of five independent experiments. *P < 0.01 compared to the agonist alone.

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