Figure 4
From: Development of thymic lymphomas in mice disrupted of Brca2 allele in the thymus
CD4 and CD8 property in thymus of dead BRCA2F11/F11; Lck-Cre mouse. T cells in thymus from one of the dead BRCA2F11/F11; Lck-Cre mice were stained with CD4-FITC and CD8-PE for flow cytometric analysis. (A) Wild-type mice show normal profile of T cell populations in the thymus; CD4 single positive, CD8 single positive, double positive and double negative cells. (B) T cells from dead BRCA2F11/F11; Lck-Cre only contain CD4 single positive cells, suggesting that it is a monoclonal thymic lymphoma.
