Figure 2 | Experimental & Molecular Medicine

Figure 2

From: A MELAS syndrome family harboring two mutations in mitochondrial genome

Figure 2

Identification of two causative missense mutations in MT48 MELAS family. (A) Sequence chromatograms of the 9957T > C (Phe251Leu) mutation in CO3 (left) and the 13849A > C (Asn505His) mutation in ND5 (right). (B) Conservation of these sequences in different species. The 9957T > C (Phe251Leu) mutation site is highly conserved and the 13849A > C (Asn505His) mutation is moderately conserved.

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