Figure 3 | Experimental & Molecular Medicine

Figure 3

From: Repeated electroconvulsive seizure induces c-Myc down-regulation and Bad inactivation in the rat frontal cortex

Figure 3

Increased immunostaining of phospho-c-Myc co-localized with immunofluorescence of Neu-N and DAPI in the rat frontal cortex after repeated ECS for 10 days. (A) Representative microscopic images taken from sections stained for phospho-c-Myc (Thr58/Ser62). All captured images were obtained 24 h after repeated sham (a, b) or ECS treatments (c, d) for 10 days. The number of cells immunostained for phospho-c-Myc (Thr58/Ser62) was higher in the E10X group than in the sham group. Magnification bar = 100 µm in a and d, and 20 µm in b and d. (B) Double-label immunofluorescence analysis was performed to determine whether the cells stained for phospho-c-Myc (Thr58/Ser62) antibody were of neuronal or glial origin. Immunofluorescence of phospho-c-Myc was co-localized with that of Neu-N and DAPI, but not with that of GFAP. Magnification bar = 20 µm.

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