Figure 4
Mucosal IgA responses induced by systemic and mucosal delivery of rAd-gB. Groups of C57BL/6 (n = 7) mice were immunized with rAd-gB (106 pfu/mouse) by either the i.m. or i.n. route three times at 7 day intervals. Seven days after the final immunization, mucosal IgA levels in samples from both the vaginal tract (A) and feces (B) were measured by ELISA. The circles on the graph represent the individual IgG levels and the height of the bar shows the average of each group (n = 7). P-values in the graphs were calculated using the Student's t-test.
